side effect of justicia carnea

Eyong EU, Umoh IB, Ebong PE, Eteng MU, Antai AB, Akpa AO. Note: A=change in absorbance, TV=total volume, SV=sample volume, TP=total protein, =molar extinction =1.34104M1 cm1. This research focused on the safety and in vivo antioxidant status of healthy albino rats exposed to J. carnea leaf ethanol extract. Faiza R, Waqas KK, Adeel M, Muhammad G. Detection of bioactive fractions of Justicia adhatoda leaves. In sub-acute toxicity study, total of thirty (30) rats were randomized into six groups of five rats per group: Group 1 served as control and was administered with 1ml of distilled water (dH2O). Accept A total number of forty two (42) male albino rats weighing between 120 and 170g were used in this study. However, caution should be taken as higher dose at 1200mg/kg could cause noticeable tissue injury. J Acute Disease. what are the pros and cons of testosterone replacement therapy? Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. The authors acknowledge the Director and staff of Peak Health Diagnostic and Research Laboratory, Ibadan, Oyo State, Nigeria, for the technical support and interpretation of the histology. The LD50 of extract was greater than 5000mg/kg body weight. The package will tell you exactly how, when, and how much feed to use. The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. We'll respect your privacy and unsubscribe at any time. long (25 cm), and showy flower plumes, 8 in. 1972;47:38994. Provided by the Springer Nature SharedIt content-sharing initiative. So lets go through this together. Despite the avalanche use of medicinal plant, preliminary toxicity studies remain essential tools to ensure safe consumption and prevent unexpected toxicity that could arise from long term exposure. One of the health benefits of justicia carnea is in boosting immune system. Differences between means were considered to be significant at (p<0.05) using LSD (Least Square Difference) post hoc test. One of the numerous nutritional benefits of justicia carnea leaves is in the possession of various forms of the B vitamins such as Vitamin B1, B2, B6, B9, and B12. Liver and kidney are the main targets of toxicants because they are respectively involved in biotransformation and excretion of xenobiotics. Regular intake can reduce your risk of liver diseases like liver cirrhosis, hepatitis and liver inflammation. This amazing, Coriander seeds as well as the leaves are widely used as spices in flavoring foods and drinks, and, Cashew leaves: health benefits and side effects of Anacardium occidentale, Fig leaves tea: Amazing benefits and best recipes, Negro pepper: 12 health benefits of uda seed and side effects. J Am Diet Assoc. Akintimehin is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. In these groups, from mild to severe order; shows observable congested portal vein, the liver parenchyma showed area of harmorrhage, the morphology of the hepatocytes appear pyknotic, some show mild fat infiltration (red arrow) the sinusoids appear fibrotic with infiltration of inflammatory red cells (red arrow). He earned B.Sc. Ewe eje as a Natural Blood booster/tonic: Due to the high concentration of iron in this leaf, it can help boost blood production by increasing the red blood cells, haemoglobin, and the blood platelets. Gas chromatography/mass spectrometry of simple coumarins, 3-phenylpropionic acids and their hydroxy and methoxy derivatives. The acute toxicity test also proved that justicia carnea leaves are safe for consumption. To use the website as intended please White blood cell counts usually increases following foreign invaders (pathogens) resulting in normal body physiological response which boost the bodys defense mechanisms [28, 29]. 2003;84:99104. DOI: https://doi.org/10.1089/ars.2007.1901. Inflammation is a complex biological response of body's tissue to harmful stimuli like infections, toxins and itself. What this means is that aside fighting anemia, justicia carnea leaves also improves your cardiovascular health by suppressing the tendency for dyslipidemia. The shrubby habit of the plant is well-suited for both containers and outside planting. It is obvious that Justicia carnea has potential antianemic, antioxidant, antidiabetic, hepatoprotective, and immune-boosting properties. Cite this article. Fertility leaves: Benefits and side effects, Guava Leaf Tea: Health Benefits of Guava Leaves, Coriander seeds: 18 benefits Coriandrum sativum fruits and seeds, Rapini: Nutritional facts, benefits, side effects and care. Microsomal lipid peroxidation. ESA conceived and designed the study. International Journal of Phytomedicine and Phytotherapy, Clinical Phytoscience Nutritional Composition of Ewe eje (Justicia carnea leaf). 2007;39(1):4484. To create additional collections, you must be a paid member of our site. Read also (Cashew leaves: health benefits and side effects of Anacardium occidentale). Too much sun can scorch the leaves, and too little will result in fewer flowers. The higher LD50 (>5000mg/kg body weight) of J. carnea leaf ethanol extract suggested that the ethanol extract is experimentally safe and not toxic. Backfill the soil gently, filling the empty space around the root ball and then press it down with your hands. 2017;16(2):21730 https://doi.org/10.17306/J.AFS.2017.0492. When it comes to fertilizing, an NPK balance of 5-10-5 will work well, encouraging blooming and strong growth. Prof. F.O. Note: A=change in absorbance, TV=total volume, SV=sample volume, =molar extinction=4020M1cm1, TP=total protein. A., Bezerra, G. A., Matos, F. J., and Viana, G. S. Antinociceptive, anti-inflammatory and bronchodilator activities of Brazilian medicinal plants containing coumarin: a comparative study. These antibodies help prevent infections and fight off diseases. Tissues were stained with haematoxylin and eosin, mounted on glass slides and examined under a standard light microscope. 15 Amazing benefits of brocoli juice and side effects. Due to the local availability, easy access and relatively low cost, medicinal plants are gaining attentions in health care programmes. Ewe eje improves the production of white blood cells and other antibodies, all which are essential for strengthening immunity. It can be used to manage diabetes consition properly. Watering depends on humidity and temperature. All analyzed dataset to support the conclusions of this article is included as tables in the uploaded supplementary files. Extraction was carried out by maceration (72h) following the method of Onoagbe et al., [13]. It also grows in some Caribbean islands, including Trinidad and Tobago . The Portal triad (blue arrow) composed of the hepatic vein and artery as well as the bile duct (PT), the well distributed hepatocytes (H) (yellow arrow) and hepatic sinusoids (black arrow) are demonstrated across study groups. In phase I, rats were randomized into 3 groups of 3 rats per group. -Amylase binding-interaction with JCAE was also investigated using fluorescence spectroscopy and molecular docking. The compound responsible for this activity is lignan. Ogbe RJ, Adoga GI, Abu AH. Different drugs are used but many depend mainly on plants and herbal products for its treatment. Chariandy, C. M., Seaforth, C. E., Phelps, R. H., Pollard, G. V., and Khambay, B. P. Screening of medicinal plants from Trinidad and Tobago for antimicrobial and insecticidal properties. This leaf replenishes your blood supply immediately. BMC Complem Altern Med. The effects of ethanol extract of J. carnea leaf on total protein concentration and antioxidant system in liver and kidney of normal wistar rat is presented in Table 4. Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. Aim. 2. After 72h of soaking, the wine (dark purplish red) colored filtrate was filtered using a double cheese cloth, concentrated under reduced pressure using rotary evaporator and subsequently water bath at 40C to obtain a slurry (dark purple) extract termed Justicia carnea ethanol extract (JCEE). https://doi.org/10.4314/njps.v19i1.32627. Another strong benefits of justicia carnea leaves is in lipid profile. Whether added to garden beds or pots, the justicia (plant) adds a colorful tropical touch and are easy to grow. Histopathological examination of liver and kidney showed mild to severe pathological lesion in a dose dependent manner. This later condition is termed insulin resistance. Water your plants deeply during growth periods, allowing the soil to dry . Therefore,it is imperative to investigate the effects of the plant on the essential biochemical indices in diabetic rats so as to establish its safety. The lush foliage and distinctive flowers make Brazilian Plume a natural for a tropical garden. This special leaf can be found around us- in our neighborhood. In which ever condition, the blood glucose level increases abnormally. In phase two, three rats were separated into 3 groups of one rat per group. It also can be used in combination with other vegetables such as the Efinrin (scent leaves), ugwu etc. Compared to the control, total protein in liver and kidney were statistically not altered except rats that were administered with 1200mg/kg JCEE that showed significant (p<0.05) decrease in the liver. This study has confirmed the safety of ethanol extract of J. carnea leaf and validates its conventional use as blood booster. Oyenihi OR, Brooks NL, Oguntibeju OO. https://doi.org/10.3390/molecules191221442. Side effects of Ewe eje (Justicia carnea leaf Side Effects). https://doi.org/10.13040/IJPSR.0975-8232. PubMed It is an awesome plant and worth your time and attention. Arch Toxicol. (2020). It is also composed of vitamins and minerals good for heart health. There should be further studies on the antidepressant activity of justicia carnea leaves. Consequently, the effects of the extract on MDA level could indicate damage to cell membrane lipids of the hepatocyte which could result to increased generation of reactive oxygen species (ROS). Justicia carnea is a popular ornamental plant, which possesses powerful medicinal values. The animals were randomly distributed into cages and allowed to acclimatize for 2 weeks in a well ventilated room under natural lighting condition. Deleting this collection CANNOT be undone. As for light exposure, keep the plant away from the full sun. Sci. The presence of blood boosting nutrients such as iron, copper, zinc and vitamin C can help prevent iron-deficiency anaemia and other anemic conditions. Inter J Biochem Cell Bio. The animals were allowed free access to rat chow and water ad libitum. We use cookies on this website, you can read about them here. Several medicinal plants such as Xylopia aethiopica [25], Tectona grandis [26] and extracts of M. indica, A. hybridus and T. occidentalis [27] have also been reported to elevate RBC, hemoglobin and packed cell volume. https://doi.org/10.1186/s40816-020-00234-4, DOI: https://doi.org/10.1186/s40816-020-00234-4. J. Appl. Also, remove old flowers to keep the plant healthy. Free radicals and antioxidants in normal physiological functions and human disease. Another plant with this benefit is fertility tree. Studies on the Phytochemical and Nutritional Composition of Aqueous Leaf Extract of Justicia Carnea and its Effect on Some Biochemical Parameters in Anaemic Rats. For a few weeks, the cutting should be watered every day to promote root development. WebMD does not provide medical advice, diagnosis or treatment. . Correspondence to Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. Ewe eje isn't capable of causing any side or negative effects if consumed moderately. 16. At this time there is not enough scientific information to determine an appropriate range of doses for Justicia pectoralis. In these groups, from mild to severe order; the renal cortex appears distorted, Renal glomeruli and dillated capsular spaces appeared collapsed with characteristic pyknosis of the mesangial cells, The renal tubules, interstitial spaces, appears distorted with presence of red inflammatory cells, hemorrhagic cells infiltrating the renal interstitial spaces as well as focal sclerosis of renal glomeruli with associated degeration of the glomerular membrane (red arrows). The species Justicia secunda Vahl belongs to the family - Acanthaceae - together with up to 600 other shrubs and herbs species. How to make Ewe eje Extracthow to prepare justicia carnea. 2013;3(4):1248 https://doi.org/10.7324/JAPS.2013.3422. View abstract. Ethnomedical study and iron content of some medicinal herbs used in traditional medicine in cote divoire for the treatment of anaemia. The roots and the leaves possess medicinal values and have been used in treating several diseases. In the kidney, SOD and MDA level were indistinguishable compared to the control except SOD level in rats that received 800mg/kg JCEE that reduced significantly (p<0.05). View abstract. Research reports it isnt capable of causing kidney and liver damage either but dont eat it raw. Details on Purple Shield plant care. One of the side-effects of some orthodox drugs used in the past had been excessive inhibition of the carbohydrate-hydrolyzing enzymes, which in turn leads to abdominal discomfort and. de Vries, J. X., Tauscher, B., and Wurzel, G. Constituents of Justicia pectoralis Jacq. The gradual decrease in the weight of organs following short-term exposure of J. carnea leaf ethanol extract may be attributed to adaptive response of the organs arising from daily dosage of the extract or its metabolites within their body. The findings show that ethanol extracts of Costus afer and Justicia carnea could operate as main antioxidants and free radical scavengers. Be sure to follow relevant directions on product labels and consult your, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Mediterranean, Low-Fat Diets Are Best for Heart Problems, Least Amount of Exercise You Need to Stay Healthy, Nerve 'Pulse' Therapy May Help Ease Sciatica, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. Blooming from early summer to fall, the flowers are attractive to hummingbirds and butterflies. 217-230. Aim. Higher doses (>500mg/kg) of extract significantly (p<0.05) increased RBC, hemoglobin and platelet compared to the control. 2013;1:38898. A multidisciplinary overview of intoxicating snuff rituals in the western hemisphere. Mr. T.S. 2018;2018:5762368. Philadelphia: WB. J Ethnopharmacol 1984;12(1):93-111. The spectacular rosy plumes of the flamingo-colored flower are distinctive and attract hummingbirds to pollinator gardens. 2003;66:1499503. Part shade is the ideal growing condition for Brazilian plumes. There are several nutritional benefits of justicia carnea leaves. Catalase activity (U/ml) was measured following the method of Sinha [17].

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